What the research examines
Methylene blue and photobiomodulation have separate research literatures. The studies discussed here provide context for DKGlow’s interest in skincare and light technologies. They do not establish the efficacy of DKGlow’s finished products or show that using our topicals with a device improves results.
Methylene blue in skin models
Xiong and colleagues’ 2017 Scientific Reports paper studied cultured human skin cells and reconstructed skin. It reported changes in oxidative-stress markers, cell growth, and skin-model properties. It was not a human clinical trial or a test of DKGlow’s formulas. Dr. Frikha-Benayed is not an author of that paper.
Photobiomodulation research
Hamblin’s 2017 AIMS Biophysics review discusses cellular mechanisms and inflammatory responses to low-intensity red and near-infrared light. Avci and colleagues’ 2013 review surveys skin-related light research. These reviews include varied study settings; their findings do not demonstrate the performance of every device in our catalog.
Dr. Frikha-Benayed’s research background
Dr. Dorra Frikha-Benayed is DKGlow’s founder and the formulator of its methylene-blue topical products. Her first-author 2016 Bone paper concerns osteocyte oxidative metabolism and mitochondrial activity. She also coauthored Poudel and colleagues’ 2024 skeletal-aging study: laboratory effects were observed, but the tested interventions did not improve bone mineral density or skeletal morphology in the mouse studies. Neither paper is a clinical trial of DKGlow skincare.
What remains unproven
Separate findings about an ingredient and light do not establish additive or synergistic benefits from combining them. Formulation, concentration, light source, exposure, and study population matter. We do not infer a skincare-and-device protocol from these papers.
Using products
Follow the directions on the product label and in the device manual. Confirm compatibility before combining a topical with a light or heating device. Contact DKGlow if you need instructions before purchasing.
Sources
Xiong et al. (2017). Scientific Reports, 7, 2475.
Hamblin MR (2017). AIMS Biophysics, 4(3), 337–361.
Avci et al. (2013). Seminars in Cutaneous Medicine and Surgery, 32(1), 41–52.
Frikha-Benayed et al. (2016). Bone, 90, 15–22.
Poudel et al. (2024). Aging (Albany NY), 16(6), 4948–4964.